Choosing one "best" book of 40 read proved to be an extremely difficult task. As Kayren pointed out, I 
do try to read a broad assortment of books which means that I may have enjoyed some books equally but for completely different reasons. For example, I found Clarence Thomas' memoir 
My Grandfather's Son to be enlightening, as it gave me a glimpse both into what an African-American faces when he/she chooses to stand with a conservative political agenda, as well as a front seat view of what was involved in Justice Thomas' confirmation as a Supreme Court justice. It's hard to compare that with 
The Last Chinese Chef by Nicole Mones, a book I found to be interesting as it discussed ancient Chinese customs and cuisine, choosing to see the romantic interests of the main character as a side story- one I wasn't very interested in, to be honest. See what I mean? How can I compare 
Godless: The Church of Liberalism by Ann Coulter to 
Bag of Bones by Stephen King?!
I've done my best.
When I'm choosing a book to read(if it hasn't been recommended by a friend), I must admit that the title draws me first. If it's a cheesy title I probably won't even pick it up. (In fact, the one I'm reading now has a terribly cheesy title, in my opinion. I'm almost embarrassed to admit I'm reading a book called 
Extreme Measures!) Next, cover artwork. It's not essential, but if it catches my eye I'm more likely to open the cover and read the spiel in there. I usually read the back cover as well, skimming for anything that hints of offensiveness or boredom. Then if I'm still iffy on it, I'll read the first paragraph. If I'm still not sure, I won't bother.
Fourteen of the books on my list are on the subjects of the Middle East, Asia, Africa and immigrants in America or are set during WWII. I'm interested in Asia in the past, Afghanistan and the Middle East in more recent history and currently, Africa as it is currently, and all settings for WWII. I haven't read any strictly historical books on the second World War, but I do have some waiting in line.
Some books come recommended, such as Safely Home, which was recommended by Lora, if I remember correctly. I read amazing reviews of Khaled Hosseini's books, as well as of Stephen King's books. I loved the former and hated the latter. Clearly, recommendations may or may not help.
But what gets me most isn't a good story, it's excellent writing. The most awesome writers can weave magic out of the mundane and typical. They don't need brilliant stories or specific genres to propel them to noteriety, they do it with the sheer beauty of their words. They have the gift of magic.
And so here are my choices for 
best book of the year, from my own reading list:
Honorable mentions:
Safely Home

Red Letters: Living a Faith That Bleeds
First Place (tie):
Bel Canto

A Thousand Splendid Suns
Worst Books of 2008:
Dishonorable mentions:
The Lovely Bones

Bag of Bones
(Note to self: don't read anything with "Bones" in the title.)
First Place:
Change of Heart
I realize the 3 books on my "worst list" are either very popular books or by popular authors. I've chosen them mostly for their offensiveness factor, as well as elements of the ridiculous. If I'd chosen them by boredom rating, 
The Alchemist would have made the list, as well as 
The Prayer Chest. Both were glorified snoozefests.
If I'd been able to choose one from this year, the only one I've read would have made it. I LOVED Cane River by Lalita Tademy. As a rule, I don't read Oprah books, but I'm glad I bent that rule in this case. A very interesting story based in fact from Louisiana, starting before the end of slavery and working up through three generations until 1936. A great novel.
Cheers!
